The Results Are In from Quest Diagnostics®

Exocrine pancreatic insufficiency: Symptoms, risk factors, and the value of pancreatic elastase testing

Episode Summary

Dr. Elif Nahas breaks down EPI symptoms, risk factors, and why pancreatic elastase testing supports timely, effective diagnosis and care.

Episode Notes

Exocrine pancreatic insufficiency (EPI) is an underrecognized but clinically significant condition that can lead to malnutrition, weight loss, and long-term complications if left undiagnosed. Fortunately, there's a noninvasive and highly specific test that can help clinicians take the guesswork out of diagnosis.

In this episode of The Results Are In, host Jen Jenkins speaks with Dr Elif Nahas, Associate Director of Pathology and Chair of the Gastrointestinal and Liver Resource Committee at Quest Diagnostics. Dr Nahas explains what EPI is, the most common symptoms, and which patients are at highest risk. She also outlines how pancreatic elastase testing works, why it’s reliable even for patients already on pancreatic enzyme replacement therapy, and how to interpret test results accurately.

Whether you're a primary care provider or a GI specialist, this episode offers clear insights into why EPI should be on your diagnostic radar and how early identification and treatment can significantly improve patient outcomes.

Follow Us

Twitter @QuestDX 
Facebook @QuestDiagnostics

Instagram @QuestDiagnostics

LinkedIn @QuestDiagnostics

Abbreviations used in episode:

EPI: Exocrine pancreatic insufficiency

AGA: American Gastroenterological Association

References mentioned in episode: 

  1. Quest Diagnostics Test Directory – Pancreatic Elastase-1, Fecal:
    https://testdirectory.questdiagnostics.com/test/test-detail/14693/pancreatic-elastase-1?cc=MASTER
  2. American Gastroenterological Association (AGA):
    https://gastro.org